My paternal grandparent's surnames were KLAMM and BRENNER and were German origin. My maternal grandparent's surnames were ANDERSON and KIMSEY. They came to northern Missouri from Virginia, so I'm calling them the southerners.
My German ancestors came to America in the 1840s, most of them from the Rhine River area near Ludwigshafen and Mannheim. Most of them went directly to the Missouri River area near Kansas City. They were farmers in Germany and farmers in America. The Missouri River area apparently reminded them of their homeland near the Rhine.
The southerners came from colonial Virginia. They soon started pushing westward through the Appalachian Mountains into what is now Kentucky. Always wanting new land, they continued to move to new territory. My ancestors came to Missouri via Virginia, Kentucky, North Carolina, Georgia.